BDBM425242 4-[1-(2-fluorophenyl) sulfonyl-3-(1-methyl- pyrazol-4-yl)pyrrolo [3,2-b]pyridin-6-yl]- 3,5-dimethyl-isoxazole::US10519177, Compound P-0121

SMILES Cc1noc(C)c1-c1cnc2c(cn(c2c1)S(=O)(=O)c1ccccc1F)-c1cnn(C)c1

InChI Key InChIKey=VMTSUMJMRDYKNY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425242   

TargetBromodomain-containing protein 4 [44-164](Human)
Plexxikon

US Patent
LigandPNGBDBM425242(US10519177, Compound P-0121 | 4-[1-(2-fluorophenyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
US Patent