BDBM425246 4-[3-(1-ethylpyrazol- 4-yl)-1-(2-fluorophenyl) sulfonyl-pyrrolo[3,2-b] pyridin-6-yl]-3,5- dimethyl-isoxazole::US10519177, Compound P-0125

SMILES CCn1cc(cn1)-c1cn(c2cc(cnc12)-c1c(C)noc1C)S(=O)(=O)c1ccccc1F

InChI Key InChIKey=XRUMILNRGXHHLK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425246   

TargetBromodomain-containing protein 4 [44-164](Human)
Plexxikon

US Patent
LigandPNGBDBM425246(US10519177, Compound P-0125 | 4-[3-(1-ethylpyrazol...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
US Patent