BDBM4258 (2-Hydroxy-3-methoxy)benzoyl- (2S,3S) -AHPBA-4(S)-Cl-Pro-NH-t-Bu::(2S,4S)-N-tert-butyl-4-chloro-1-[(2S,3S)-2-hydroxy-3-[(2-hydroxy-3-methoxyphenyl)formamido]-4-phenylbutanoyl]pyrrolidine-2-carboxamide::AHPBA 27::CHEMBL113810

SMILES COc1cccc(C(=O)N[C@@H](Cc2ccccc2)[C@H](O)C(=O)N2C[C@@H](Cl)C[C@H]2C(=O)NC(C)(C)C)c1O

InChI Key InChIKey=QCUVBKBFHLESBR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4258   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4258((2-Hydroxy-3-methoxy)benzoyl- (2S,3S) -AHPBA-4(S)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4258((2-Hydroxy-3-methoxy)benzoyl- (2S,3S) -AHPBA-4(S)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed