BDBM425938 US10512644, Compound 6-O-mPEG8-Nalbuphine

SMILES COCCOCCOCCOCCOCCOCCOCCOCCO[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CCC1)c45

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 425938   

TargetMu-type opioid receptor(Human)
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425938(US10512644, Compound 6-O-mPEG8-Nalbuphine)
Affinity DataKi:  79.5nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
US Patent

TargetDelta-type opioid receptor(Human)
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425938(US10512644, Compound 6-O-mPEG8-Nalbuphine)
Affinity DataKi:  168nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
US Patent