BDBM425944 2,6-Difluoro-N-isopropyl-4-(3-{[(trans-2-phenylcyclopropyl)amino]methyl}azetidin-1-yl)benzamide::US10513493, Example 7

SMILES CC(C)NC(=O)c1c(F)cc(cc1F)N1CC(CNC2CC2c2ccccc2)C1

InChI Key InChIKey=JAKHQXGBHULLJV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425944   

TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM425944(2,6-Difluoro-N-isopropyl-4-(3-{[(trans-2-phenylcyc...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
US Patent