BDBM426494 US10543199, Compound 28

SMILES C[C@@H]1Oc2cc(cnc2N)-c2c(CN(C)C(=O)c3ccc(F)cc13)nn(C)c2C#N

InChI Key InChIKey=IIXWYSCJSQVBQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426494   

TargetALK tyrosine kinase receptor(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM426494(US10543199, Compound 28)
Affinity DataIC50: 1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM426494(US10543199, Compound 28)
Affinity DataIC50: 55nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent