BDBM426673 N-(3-(5-amino-6-(2-fluoro-4-((4- (trifluoromethyl)pyridin-2-yl)oxy)phenyl) quinazolin-8-yl)phenyl)acrylamide::US10544106, Compound C187::US11208388, Example 189

SMILES Nc1c(cc(-c2cccc(NC(=O)C=C)c2)c2ncncc12)-c1ccc(Oc2cc(ccn2)C(F)(F)F)cc1F

InChI Key InChIKey=ASDVPZXJWNVKJR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426673   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426673(N-(3-(5-amino-6-(2-fluoro-4-((4- (trifluoromethyl)...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426673(N-(3-(5-amino-6-(2-fluoro-4-((4- (trifluoromethyl)...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent