BDBM426687 N-(3-(2-amino-6-(pyridin-3-yl)quinazolin-8- yl)phenyl)acrylamide::US10544106, Compound C035

SMILES Nc1ncc2cc(cc(-c3cccc(NC(=O)C=C)c3)c2n1)-c1cccnc1

InChI Key InChIKey=BGSRGGZOBOKNGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426687   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426687(N-(3-(2-amino-6-(pyridin-3-yl)quinazolin-8- yl)phe...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent