BDBM426695 4-(5-(1-acryloylpyrrolidin-3-yl)pyrrolo[1,2- c]pyrimidin-7-yl)-N-(4-fluoropyridin-2- yl)benzamide::US10544106, Compound C065

SMILES Fc1ccnc(NC(=O)c2ccc(cc2)-c2cc(C3CCN(C3)C(=O)C=C)c3ccncn23)c1

InChI Key InChIKey=GZTCKUSPOANOOP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426695   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426695(4-(5-(1-acryloylpyrrolidin-3-yl)pyrrolo[1,2- c]pyr...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent