BDBM426701 1-(3-(2-amino-6-(4-phenoxyphenyl)quinazolin- 8-yl)pyrrolidin-1-yl)prop-2-en-1-one::US10544106, Compound C078

SMILES Nc1ncc2cc(cc(C3CCN(C3)C(=O)C=C)c2n1)-c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=IPDIERJKSWJBBO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426701   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426701(1-(3-(2-amino-6-(4-phenoxyphenyl)quinazolin- 8-yl)...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent