BDBM426702 N-(3-(6-(6-(3-fluorophenoxy)pyridin-3- yl)quinazolin-8-yl)phenyl)acrylamide::US10544106, Compound C086::US11208388, Example 91

SMILES Fc1cccc(Oc2ccc(cn2)-c2cc(-c3cccc(NC(=O)C=C)c3)c3ncncc3c2)c1

InChI Key InChIKey=HQCNRHNULPKTMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426702   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426702(N-(3-(6-(6-(3-fluorophenoxy)pyridin-3- yl)quinazol...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426702(N-(3-(6-(6-(3-fluorophenoxy)pyridin-3- yl)quinazol...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent