BDBM426708 N-(3-(6-(4-((3-chloropyridin-2-yl)oxy)-2- fluorophenyl)quinazolin-8-yl)phenyl)acrylamide::US10544106, Compound C106::US11208388, Example 106

SMILES Fc1cc(Oc2ncccc2Cl)ccc1-c1cc(-c2cccc(NC(=O)C=C)c2)c2ncncc2c1

InChI Key InChIKey=FPKILVKKFMUZRD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426708   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426708(N-(3-(6-(4-((3-chloropyridin-2-yl)oxy)-2- fluoroph...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426708(N-(3-(6-(4-((3-chloropyridin-2-yl)oxy)-2- fluoroph...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent