BDBM426710 N-(3-(6-(2-fluoro-4-(pyridin-2-yloxy)phenyl) quinazolin-8-yl)phenyl)acrylamide::US10544106, Compound C112::US11208388, Example 112

SMILES Fc1cc(Oc2ccccn2)ccc1-c1cc(-c2cccc(NC(=O)C=C)c2)c2ncncc2c1

InChI Key InChIKey=RDHHNNSMLWSPLA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426710   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426710(N-(3-(6-(2-fluoro-4-(pyridin-2-yloxy)phenyl) quina...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426710(N-(3-(6-(2-fluoro-4-(pyridin-2-yloxy)phenyl) quina...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent