BDBM426711 4-(8-(3-acrylamidophenyl)quinazolin-6-yl)-3- chloro-N-(4-(trifluoromethyl)pyridin-2- yl)benzamide::US10544106, Compound C116::US11208388, Example 116

SMILES FC(F)(F)c1ccnc(NC(=O)c2ccc(c(Cl)c2)-c2cc(-c3cccc(NC(=O)C=C)c3)c3ncncc3c2)c1

InChI Key InChIKey=GQKDUGDNUQVOPY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426711   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426711(4-(8-(3-acrylamidophenyl)quinazolin-6-yl)-3- chlor...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426711(4-(8-(3-acrylamidophenyl)quinazolin-6-yl)-3- chlor...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent