BDBM426712 N-(3-(6-(4-(pyridin-3-yloxy)phenyl) quinazolin-8-yl)phenyl)acrylamide::US10544106, Compound C117::US11208388, Example 117

SMILES C=CC(=O)Nc1cccc(c1)-c1cc(cc2cncnc12)-c1ccc(Oc2cccnc2)cc1

InChI Key InChIKey=GSFXLSBIPKBPBJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426712   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426712(N-(3-(6-(4-(pyridin-3-yloxy)phenyl) quinazolin-8-y...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426712(N-(3-(6-(4-(pyridin-3-yloxy)phenyl) quinazolin-8-y...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent