BDBM426716 4-(8-(3-acrylamidophenyl)quinazolin-6-yl)- 3-fluoro-N-(4-(trifluoromethyl)pyridin-2- yl)benzamide::US10544106, Compound C129::US11208388, Example 129

SMILES Fc1cc(ccc1-c1cc(-c2cccc(NC(=O)C=C)c2)c2ncncc2c1)C(=O)Nc1cc(ccn1)C(F)(F)F

InChI Key InChIKey=CREQRNYFYAZIMJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426716   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426716(4-(8-(3-acrylamidophenyl)quinazolin-6-yl)- 3-fluor...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426716(4-(8-(3-acrylamidophenyl)quinazolin-6-yl)- 3-fluor...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent