BDBM426724 N-(3-(2-amino-6-(3-fluoro-4-(pyridin-2- yloxy)phenyl)quinazolin-8-yl)phenyl)acrylamide::US10544106, Compound C158::US11208388, Example 158

SMILES Nc1ncc2cc(cc(-c3cccc(NC(=O)C=C)c3)c2n1)-c1ccc(Oc2ccccn2)c(F)c1

InChI Key InChIKey=ITDXMYADOCRWRB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426724   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426724(N-(3-(2-amino-6-(3-fluoro-4-(pyridin-2- yloxy)phen...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426724(N-(3-(2-amino-6-(3-fluoro-4-(pyridin-2- yloxy)phen...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent