BDBM426725 4-(5-(1-acryloylpyrrolidin-3-yl)pyrrolo[1,2- c]pyrimidin-7-yl)-N-(4-cyanopyridin-2- yl)benzamide::US10544106, Compound C161::US11208388, Example 161

SMILES C=CC(=O)N1CCC(C1)c1cc(-c2ccc(cc2)C(=O)Nc2cc(ccn2)C#N)n2cnccc12

InChI Key InChIKey=FJOFEDQJKITORM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426725   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426725(4-(5-(1-acryloylpyrrolidin-3-yl)pyrrolo[1,2- c]pyr...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426725(4-(5-(1-acryloylpyrrolidin-3-yl)pyrrolo[1,2- c]pyr...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent