BDBM426739 1-(3-(5-amino-3-(4-((4-(trifluoromethyl)pyridin- 2-yl)oxy)phenyl)imidazo[1,5-c]pyrimidin-1- yl)pyrrolidin-1-yl)prop-2-en-1-one::US10544106, Compound C196::US11208388, Example 198

SMILES Nc1nccc2c(nc(-c3ccc(Oc4cc(ccn4)C(F)(F)F)cc3)n12)C1CCN(C1)C(=O)C=C

InChI Key InChIKey=WQAZCDSGMLSTGI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426739   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426739(1-(3-(5-amino-3-(4-((4-(trifluoromethyl)pyridin- 2...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandPNGBDBM426739(1-(3-(5-amino-3-(4-((4-(trifluoromethyl)pyridin- 2...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent