BDBM429487 1-Methyl-N-(methylsulfonyl)-3-(m-tolyl)-1H-indole-6-carboxamide::US10550080, Example 15
SMILES Cc1cccc(c1)-c1cn(C)c2cc(ccc12)C(=O)NS(C)(=O)=O
InChI Key InChIKey=AZGUAMOGUBTAQX-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 429487
Affinity DataIC50: 375nMAssay Description:Ion Works Barracuda population patch clamp (PPC). PPC measurements were performed using an IonWorks Barracuda instrument (Molecular Devices Corporati...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells after 600 secs at -60 mV holding potential by ion works barracuda population patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 943nMAssay Description:hNaV1.7 binding affinities were determined with a filtration binding assay using purified membranes from HEK293 cells stably expressing hNaV1.7. HEK2...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 600 secs at -50 mV holding potential by ion works barracuda population patch clamp methodMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Human)
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Ion Works Barracuda population patch clamp (PPC). PPC measurements were performed using an IonWorks Barracuda instrument (Molecular Devices Corporati...More data for this Ligand-Target Pair