BDBM43061 (Z)-3-[4-(diethylamino)-2-propoxy-phenyl]-2-(6-methyl-1H-benzimidazol-2-yl)acrylonitrile::(Z)-3-[4-(diethylamino)-2-propoxy-phenyl]-2-(6-methyl-1H-benzimidazol-2-yl)prop-2-enenitrile::(Z)-3-[4-(diethylamino)-2-propoxyphenyl]-2-(6-methyl-1H-benzimidazol-2-yl)-2-propenenitrile::(Z)-3-[4-(diethylamino)-2-propoxyphenyl]-2-(6-methyl-1H-benzimidazol-2-yl)prop-2-enenitrile::3-[4-(diethylamino)-2-propoxyphenyl]-2-(5-methyl-1H-benzimidazol-2-yl)acrylonitrile::MLS000578627::SMR000186120::cid_5722655

SMILES CCCOc1cc(ccc1C=C(C#N)c1nc2ccc(C)cc2[nH]1)N(CC)CC

InChI Key InChIKey=JUMIAJFEKXTUFO-UHFFFAOYSA-N

Data  2 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 43061   

TargetG-protein coupled receptor 35(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM43061(3-[4-(diethylamino)-2-propoxyphenyl]-2-(5-methyl-1...)
Affinity DataIC50: 573nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM43061(3-[4-(diethylamino)-2-propoxyphenyl]-2-(5-methyl-1...)
Affinity DataEC50:  1.19E+3nMAssay Description:Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetGlycoprotein 42(HHV-4)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM43061(3-[4-(diethylamino)-2-propoxyphenyl]-2-(5-methyl-1...)
Affinity DataIC50: 1.27E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM43061(3-[4-(diethylamino)-2-propoxyphenyl]-2-(5-methyl-1...)
Affinity DataEC50:  3.19E+4nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay
TargetNuclear receptor coactivator 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43061(3-[4-(diethylamino)-2-propoxyphenyl]-2-(5-methyl-1...)
Affinity DataEC50: >7.94E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetNuclear receptor coactivator 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43061(3-[4-(diethylamino)-2-propoxyphenyl]-2-(5-methyl-1...)
Affinity DataEC50: >7.94E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetNuclear receptor coactivator 3(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43061(3-[4-(diethylamino)-2-propoxyphenyl]-2-(5-methyl-1...)
Affinity DataEC50: >7.94E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center http://molscreen.florida.scripps.edu/ Center Affiliation: The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay