BDBM430859 US10550102, Example 3b

SMILES CCOC(=O)c1cnn(c1C(F)(F)F)-c1cccc(n1)-c1cccc2CCC(Oc3ccc(cc3C)C3CCN(CC3)C(=O)C3CC3)c12

InChI Key InChIKey=JCDHXZLCXOEAIM-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430859   

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Human)
Novartis

US Patent

LigandBDBM430859(US10550102, Example 3b)Copy SMILESCopy InChI

Affinity DataEC50:  6.90nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/20/2020
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL