BDBM430861 US10550102, Example 4a

SMILES OC(=O)c1cnn(c1C(F)(F)F)-c1cccc(n1)-c1cccc2CCC(Oc3ccc4CN(Cc5ccccn5)CCc4c3)c12

InChI Key InChIKey=DYDRUUIDSBBBCY-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430861   

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Human)
Novartis

US Patent

LigandBDBM430861(US10550102, Example 4a)Copy SMILESCopy InChI

Affinity DataEC50:  2.40nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/20/2020
Entry Details
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