BDBM430893 US10550102, Example 18

SMILES CCc1c(cnn1-c1cccc(n1)-c1cccc2CCN(Cc3ccc(cc3C)C3CCN(CC3)C(=O)[C@H](C)O)c12)C(O)=O

InChI Key InChIKey=AFVFPZHPDMHXET-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430893   

LigandPNGBDBM430893(US10550102, Example 18)
Affinity DataEC50:  1.40nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent