BDBM432075 US10577308, Compound 536

SMILES Cc1cccc(C)c1OCCCNCc1ccccc1-c1ccccc1

InChI Key InChIKey=GLOFDSICARPTQQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 432075   

TargetSodium channel protein type 2 subunit alpha(Human)
The Florey Institute

US Patent
LigandPNGBDBM432075(US10577308, Compound 536)
Affinity DataIC50: 400nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetSodium channel protein type 2 subunit alpha(Human)
The Florey Institute

US Patent
LigandPNGBDBM432075(US10577308, Compound 536)
Affinity DataIC50: 400nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
The Florey Institute

US Patent
LigandPNGBDBM432075(US10577308, Compound 536)
Affinity DataIC50: 1.30E+3nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
The Florey Institute

US Patent
LigandPNGBDBM432075(US10577308, Compound 536)
Affinity DataIC50: 1.30E+3nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
The Florey Institute

US Patent
LigandPNGBDBM432075(US10577308, Compound 536)
Affinity DataIC50: 2.14E+4nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetSodium channel protein type 2 subunit alpha(Human)
The Florey Institute

US Patent
LigandPNGBDBM432075(US10577308, Compound 536)
Affinity DataIC50: 3.00E+4nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent