BDBM433640 5-Chloro-2-[1-(1-ethyl-1H-pyrazole-4-carbonyl)-3-methoxypiperidin-3-yl]-3-(trifluoromethyl)pyridine::US10562882, Example 32

SMILES CCn1cc(cn1)C(=O)N1CCCC(C1)(OC)c1ncc(Cl)cc1C(F)(F)F

InChI Key InChIKey=PJCDKUUHXVTCKL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433640   

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM433640(5-Chloro-2-[1-(1-ethyl-1H-pyrazole-4-carbonyl)-3-m...)
Affinity DataIC50: 1.88E+3nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent