BDBM433663 5-Chloro-2-[1-(1-ethyl-1H-pyrazole-4-carbonyl)-3-fluoropiperidin-3-yl]-3-methylpyridine::US10562882, Example 41

SMILES CCn1cc(cn1)C(=O)N1CCCC(F)(C1)c1ncc(Cl)cc1C

InChI Key InChIKey=BCBHVZYAERSMIX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433663   

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM433663(5-Chloro-2-[1-(1-ethyl-1H-pyrazole-4-carbonyl)-3-f...)
Affinity DataIC50: 2.39E+3nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent