BDBM4337 2-[(4-formylphenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 21

SMILES O=[#6]-c1ccc(\[#6]=[#6](/C#N)C#N)cc1

InChI Key InChIKey=NPBDQTRGJPQJNS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4337   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM4337(2-[(4-formylphenyl)methylidene]propanedinitrile | ...)
Affinity DataKi:  2.00E+4nM ΔG°:  -6.34kcal/mole IC50: 6.00E+4nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2005
Entry Details Article
PubMed