BDBM433854 US10562878, Compound 280::US10562878, Compound 283

SMILES CCC1(O)CCC(CN(C)C)(CC1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=SJTJLLXHBQCTJD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 433854   

TargetSodium-dependent serotonin transporter(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433854(US10562878, Compound 283 | US10562878, Compound 28...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetNeuroepithelial cell-transforming gene 1 protein(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433854(US10562878, Compound 283 | US10562878, Compound 28...)
Affinity DataIC50: 371nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433854(US10562878, Compound 283 | US10562878, Compound 28...)
Affinity DataIC50: 242nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433854(US10562878, Compound 283 | US10562878, Compound 28...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetNeuroepithelial cell-transforming gene 1 protein(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433854(US10562878, Compound 283 | US10562878, Compound 28...)
Affinity DataIC50: 41nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433854(US10562878, Compound 283 | US10562878, Compound 28...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent