BDBM434596 US10562902, Compound 2

SMILES CC(C)Nc1nc(Nc2cc(C)ns2)nc2ccn(-c3cnn(C)c3)c12

InChI Key InChIKey=AUNIKUGMRZIBAI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 434596   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Beijing Hanmi Pharmaceutical

US Patent
LigandPNGBDBM434596(US10562902, Compound 2)
Affinity DataIC50: 100nMAssay Description:IRAK4 kinase (purchased from Life Technologies, Cat. No.: PR5612U) was diluted to 2 folds of the final concentration (the final concentration is 0.76...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent