BDBM434734 US10562902, Compound 140

SMILES Cn1cc(cn1)-n1ccc2nc(Nc3cc(cs3)C(=O)NCC3CCOCC3)nc(O[C@@H]3CCOC3)c12

InChI Key InChIKey=GSVJWAOJLRDCSC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 434734   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Beijing Hanmi Pharmaceutical

US Patent
LigandPNGBDBM434734(US10562902, Compound 140)
Affinity DataIC50: 100nMAssay Description:IRAK4 kinase (purchased from Life Technologies, Cat. No.: PR5612U) was diluted to 2 folds of the final concentration (the final concentration is 0.76...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent