BDBM435939 (+-)-5-[2-Chloro-3-[(2,2-difluorocyclopropyl)methoxy]phenyl]-1,3-::US10611730, Example 111

SMILES FC1(F)CC1COc1cccc(c1Cl)-c1ccc2[nH]c(=O)[nH]c2c1

InChI Key InChIKey=MOFGOIIRKOZTLI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435939   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435939(US10611730, Example 111 | (+-)-5-[2-Chloro-3-[(2,2...)
Affinity DataIC50: 50.1nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent