BDBM437089 2-[6-[3-(Difluoromethyl)phenyl]-3-methyl-2-oxo-imidazo[4,5-b]pyridin-1-yl]- N,N-dimethyl-acetamide::US10617676, Example 426::US11207298, Example 426

SMILES CN(C)C(=O)Cn1c2cc(cnc2n(C)c1=O)-c1cccc(c1)C(F)F

InChI Key InChIKey=ZMZYUZTXEXMVIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437089   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM437089(US10617676, Example 426 | 2-[6-[3-(Difluoromethyl)...)
Affinity DataIC50: 19nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM437089(US10617676, Example 426 | 2-[6-[3-(Difluoromethyl)...)
Affinity DataIC50: 19nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent