BDBM437720 US10597382, Example 3::US10597382, Example 4

SMILES C[C@H](COC(C)=O)n1nnnc1-c1cccc(n1)N1Cc2ccc(cc2C1=O)-n1cnc(c1)C1CC1

InChI Key InChIKey=PREROSXPIHASHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437720   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM437720(US10597382, Example 4 | US10597382, Example 3)
Affinity DataIC50: 55nMAssay Description:ASK1 kinase was from Thermofisher (Catalogue # PV4011), ATP was from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained from Cisbio (B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM437720(US10597382, Example 4 | US10597382, Example 3)
Affinity DataIC50: 550nMAssay Description:ASK1 kinase was from Thermofisher (Catalogue # PV4011), ATP was from Sigma (Catalogue # A7699), HTRF KinEASE Assay System was obtained from Cisbio (B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent