BDBM438765 US10618914, Compound 2b::US11111253, Compound 2b

SMILES Clc1ccc(cc1)C1=Nn2c(SC1)nnc2-c1cc(n[nH]1)-c1ccccc1

InChI Key InChIKey=JVYMSPPKDODTNF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 438765   

TargetSignal transducer and activator of transcription 3(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM438765(US10618914, Compound 2b | US11111253, Compound 2b)
Affinity DataIC50: 2.68E+4nMAssay Description:Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, HRMS),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetSignal transducer and activator of transcription 1-alpha/beta(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM438765(US10618914, Compound 2b | US11111253, Compound 2b)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, HRMS),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetSignal transducer and activator of transcription 3(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM438765(US10618914, Compound 2b | US11111253, Compound 2b)
Affinity DataIC50: 9.60E+3nMAssay Description:Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, FIRMS)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
Go to US Patent

TargetSignal transducer and activator of transcription 1-alpha/beta(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM438765(US10618914, Compound 2b | US11111253, Compound 2b)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, FIRMS)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
Go to US Patent

TargetSignal transducer and activator of transcription 3(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM438765(US10618914, Compound 2b | US11111253, Compound 2b)
Affinity DataIC50: 9.60E+3nMAssay Description:Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, FIRMS)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
Go to US Patent

TargetSignal transducer and activator of transcription 1-alpha/beta(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM438765(US10618914, Compound 2b | US11111253, Compound 2b)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, FIRMS)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
Go to US Patent