BDBM439342 US10604535, Example 51

SMILES CN1c2ccccc2CC[C@H](NC(=O)c2nnc([nH]2)C2CCc3ccccc23)C1=O

InChI Key InChIKey=JNHKDXJTBAYFHB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 439342   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Denali Therapeutics

US Patent
LigandPNGBDBM439342(US10604535, Example 51)
Affinity DataIC50: 1.00E+3nMAssay Description:Fluorescent polarization binding assay was performed in polystyrene low volume 384-well black plate, at Room Temperature (RT) in a final volume of 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2020
Entry Details
Go to US Patent