BDBM439657 US10633389, Example 56-1::US20230279020, Example 56-1

SMILES CNCC(O)COc1cccc(c1)-c1nc(cc(n1)-c1ccc(cc1)S(C)(=O)=O)N(C)CCC#N

InChI Key InChIKey=PTDWHYGSMPCSKI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 439657   

TargetHistone-arginine methyltransferase CARM1(Human)
Epizyme

US Patent
LigandPNGBDBM439657(US10633389, Example 56-1 | US20230279020, Example ...)
Affinity DataIC50: 100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween 20, prepared on the day of use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
Go to US Patent

TargetHistone-arginine methyltransferase CARM1(Human)
Epizyme

US Patent
LigandPNGBDBM439657(US10633389, Example 56-1 | US20230279020, Example ...)
Affinity DataIC50: 100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween 20, prepared on the day of use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent