BDBM441032 US10640486, Example 79

SMILES Nc1nccc2[C@@H](CCc12)NC(=O)c1cnn(Cc2ccc(nc2)N2CC3CCC3C2)c1

InChI Key InChIKey=BFYSKNJTLQKOAK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 441032   

TargetTyrosine-protein kinase BTK(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM441032(US10640486, Example 79)
Affinity DataIC50: 8nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Flouresence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent