BDBM4416 4-Anilidoquinazoline deriv. 32b::6,7-dimethoxy-2-N,4-N-bis(4-methylphenyl)quinazoline-2,4-diamine

SMILES COc1cc2nc(Nc3ccc(C)cc3)nc(Nc3ccc(C)cc3)c2cc1OC

InChI Key InChIKey=CIHXAAJUXLYSLJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4416   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM4416(6,7-dimethoxy-2-N,4-N-bis(4-methylphenyl)quinazoli...)
Affinity DataIC50: 5.00E+4nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2005
Entry Details Article
PubMed