BDBM4417 4-Anilidoquinazoline deriv. 33b::N-(3-chlorophenyl)-6,7-dimethoxy-2-(4-methylpiperazin-1-yl)quinazolin-4-amine

SMILES COc1cc2nc(nc(Nc3cccc(Cl)c3)c2cc1OC)N1CCN(C)CC1

InChI Key InChIKey=APICIERXNBVOHG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4417   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM4417(N-(3-chlorophenyl)-6,7-dimethoxy-2-(4-methylpipera...)
Affinity DataIC50: 5.00E+4nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2005
Entry Details Article
PubMed