BDBM441783 US10640533, Identification number CX13-501::US10640533, Table 1.30

SMILES COC[C@H](NC(=O)c1cc(C)on1)C(=O)N[C@@H](Cc1ccncc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1

InChI Key InChIKey=DGGJPJSQJJFTRY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 441783   

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandPNGBDBM441783(US10640533, Table 1.30 | US10640533, Identificatio...)
Affinity DataIC50: 392nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent

TargetProteasome subunit beta type-1(Human)
Centrax International

US Patent
LigandPNGBDBM441783(US10640533, Table 1.30 | US10640533, Identificatio...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent

TargetTransmembrane protease serine 11D(Human)
Centrax International

US Patent
LigandPNGBDBM441783(US10640533, Table 1.30 | US10640533, Identificatio...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandPNGBDBM441783(US10640533, Table 1.30 | US10640533, Identificatio...)
Affinity DataIC50: 113nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent

TargetProteasome subunit beta type-1(Human)
Centrax International

US Patent
LigandPNGBDBM441783(US10640533, Table 1.30 | US10640533, Identificatio...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent

TargetTransmembrane protease serine 11D(Human)
Centrax International

US Patent
LigandPNGBDBM441783(US10640533, Table 1.30 | US10640533, Identificatio...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent