BDBM442940 US10653688, Compound 118

SMILES CC(C)N1CCC(CC1)Nc1cncc(n1)-c1ccc2cnc(NC(=O)C3CCCC3)cc2c1

InChI Key InChIKey=ZFQVLLAPLVLNPZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 442940   

LigandPNGBDBM442940(US10653688, Compound 118)
Affinity DataEC50:  1nMAssay Description:The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies a Divis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Samumed

US Patent
LigandPNGBDBM442940(US10653688, Compound 118)
Affinity DataEC50:  78nMAssay Description:The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies a Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent