BDBM442984 2-(2-chlorophenyl)-N-hydroxy-1,3- benzoxazole-5-carboxamide::US10654814, Example 12

SMILES ONC(=O)c1ccc2oc(nc2c1)-c1ccccc1Cl

InChI Key InChIKey=SOQHGPLOGBSSPZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 442984   

TargetHistone deacetylase 6(Human)
Kancera

US Patent
LigandPNGBDBM442984(US10654814, Example 12 | 2-(2-chlorophenyl)-N-hydr...)
Affinity DataIC50: 5nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Kancera

US Patent
LigandPNGBDBM442984(US10654814, Example 12 | 2-(2-chlorophenyl)-N-hydr...)
Affinity DataIC50: 5nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Kancera

US Patent
LigandPNGBDBM442984(US10654814, Example 12 | 2-(2-chlorophenyl)-N-hydr...)
Affinity DataIC50: 560nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Kancera

US Patent
LigandPNGBDBM442984(US10654814, Example 12 | 2-(2-chlorophenyl)-N-hydr...)
Affinity DataIC50: 880nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Kancera

US Patent
LigandPNGBDBM442984(US10654814, Example 12 | 2-(2-chlorophenyl)-N-hydr...)
Affinity DataIC50: 1.20E+3nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Kancera

US Patent
LigandPNGBDBM442984(US10654814, Example 12 | 2-(2-chlorophenyl)-N-hydr...)
Affinity DataIC50: 5.20E+4nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent