BDBM443023 N-hydroxy-2-[4-(1- methylethyl)phenyl]-1- benzothiophene-6-carboxamide::US10654814, Example 88

SMILES CC(C)c1ccc(cc1)-c1cc2ccc(cc2s1)C(=O)NO

InChI Key InChIKey=MAIAQNBLEGJEJE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 443023   

TargetHistone deacetylase 6(Human)
Kancera

US Patent
LigandPNGBDBM443023(N-hydroxy-2-[4-(1- methylethyl)phenyl]-1- benzothi...)
Affinity DataIC50: 14nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Kancera

US Patent
LigandPNGBDBM443023(N-hydroxy-2-[4-(1- methylethyl)phenyl]-1- benzothi...)
Affinity DataIC50: 37nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Kancera

US Patent
LigandPNGBDBM443023(N-hydroxy-2-[4-(1- methylethyl)phenyl]-1- benzothi...)
Affinity DataIC50: 1.10E+3nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Kancera

US Patent
LigandPNGBDBM443023(N-hydroxy-2-[4-(1- methylethyl)phenyl]-1- benzothi...)
Affinity DataIC50: 1.00E+4nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Kancera

US Patent
LigandPNGBDBM443023(N-hydroxy-2-[4-(1- methylethyl)phenyl]-1- benzothi...)
Affinity DataIC50: 1.40E+4nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Kancera

US Patent
LigandPNGBDBM443023(N-hydroxy-2-[4-(1- methylethyl)phenyl]-1- benzothi...)
Affinity DataIC50: 2.60E+4nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent