BDBM443098 N-hydroxy-2-(3-methoxyphenyl)-1- benzofuran-6-carboxamide::US10654814, Example 285

SMILES COc1cccc(c1)-c1cc2ccc(cc2o1)C(=O)NO

InChI Key InChIKey=FDUWAKJKLASRSS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 443098   

TargetHistone deacetylase 6(Human)
Kancera

US Patent
LigandPNGBDBM443098(US10654814, Example 285 | N-hydroxy-2-(3-methoxyph...)
Affinity DataIC50: 4nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Kancera

US Patent
LigandPNGBDBM443098(US10654814, Example 285 | N-hydroxy-2-(3-methoxyph...)
Affinity DataIC50: 4nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Kancera

US Patent
LigandPNGBDBM443098(US10654814, Example 285 | N-hydroxy-2-(3-methoxyph...)
Affinity DataIC50: 210nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Kancera

US Patent
LigandPNGBDBM443098(US10654814, Example 285 | N-hydroxy-2-(3-methoxyph...)
Affinity DataIC50: 470nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Kancera

US Patent
LigandPNGBDBM443098(US10654814, Example 285 | N-hydroxy-2-(3-methoxyph...)
Affinity DataIC50: 640nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Kancera

US Patent
LigandPNGBDBM443098(US10654814, Example 285 | N-hydroxy-2-(3-methoxyph...)
Affinity DataIC50: 6.90E+3nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent