BDBM443101 N-hydroxy-2-[4-(6-methoxypyridin- 3-yl)phenyl]-1,3-benzoxazole-5- carboxamide::US10654814, Example 27

SMILES COc1ccc(cn1)-c1ccc(cc1)-c1nc2cc(ccc2o1)C(=O)NO

InChI Key InChIKey=SJVMHCKWSVQJIO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 443101   

TargetHistone deacetylase 6(Human)
Kancera

US Patent
LigandPNGBDBM443101(US10654814, Example 27 | N-hydroxy-2-[4-(6-methoxy...)
Affinity DataIC50: 3nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Kancera

US Patent
LigandPNGBDBM443101(US10654814, Example 27 | N-hydroxy-2-[4-(6-methoxy...)
Affinity DataIC50: 820nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Kancera

US Patent
LigandPNGBDBM443101(US10654814, Example 27 | N-hydroxy-2-[4-(6-methoxy...)
Affinity DataIC50: 2.00E+3nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Kancera

US Patent
LigandPNGBDBM443101(US10654814, Example 27 | N-hydroxy-2-[4-(6-methoxy...)
Affinity DataIC50: 2.00E+5nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Kancera

US Patent
LigandPNGBDBM443101(US10654814, Example 27 | N-hydroxy-2-[4-(6-methoxy...)
Affinity DataIC50: 2.00E+5nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent