BDBM443106 2-[2-fluoro-4-(6-methoxypyridin-3- yl)phenyl]-N-hydroxy-1,3- benzoxazole-5-carboxamide::US10654814, Example 176

SMILES COc1ccc(cn1)-c1ccc(-c2nc3cc(ccc3o2)C(=O)NO)c(F)c1

InChI Key InChIKey=ZPXAGNZHTWVGJU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 443106   

TargetHistone deacetylase 6(Human)
Kancera

US Patent
LigandPNGBDBM443106(US10654814, Example 176 | 2-[2-fluoro-4-(6-methoxy...)
Affinity DataIC50: 16nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Kancera

US Patent
LigandPNGBDBM443106(US10654814, Example 176 | 2-[2-fluoro-4-(6-methoxy...)
Affinity DataIC50: 384nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Kancera

US Patent
LigandPNGBDBM443106(US10654814, Example 176 | 2-[2-fluoro-4-(6-methoxy...)
Affinity DataIC50: 960nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Kancera

US Patent
LigandPNGBDBM443106(US10654814, Example 176 | 2-[2-fluoro-4-(6-methoxy...)
Affinity DataIC50: 2.00E+5nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Kancera

US Patent
LigandPNGBDBM443106(US10654814, Example 176 | 2-[2-fluoro-4-(6-methoxy...)
Affinity DataIC50: 2.00E+5nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent