BDBM443285 7-(4-Cyanophenyl)-2- oxo-1,4-dihydro-2H- spiro[pyrido[2,3- b]pyrazine-3,3'- pyrrolidine]- 1'-carbonitrile::US10654853, Example 58::US11236092, Example 58

SMILES O=C1Nc2cc(cnc2NC11CCN(C1)C#N)-c1ccc(cc1)C#N

InChI Key InChIKey=TZEUAYCHXZDRJE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 443285   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM443285(US10654853, Example 58 | 7-(4-Cyanophenyl)-2- oxo-...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM443285(US10654853, Example 58 | 7-(4-Cyanophenyl)-2- oxo-...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2021
Entry Details
US Patent