BDBM443294 (R)-2'-Oxo-6'- phenyl-1',4'- dihydro-2'H- spiro[pyrrolidine- 3,3'- quinoline]-1- carbonitrile::US10654853, Example 67::US11236092, Example 67

SMILES O=C1Nc2ccc(cc2C[C@]11CCN(C1)C#N)-c1ccccc1

InChI Key InChIKey=JJRODOFXOSSRAM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 443294   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM443294(US10654853, Example 67 | (R)-2'-Oxo-6'- phenyl-1',...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2021
Entry Details
US Patent

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM443294(US10654853, Example 67 | (R)-2'-Oxo-6'- phenyl-1',...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent