BDBM445317 US10669239, Compound 44b

SMILES Cc1ncc(cn1)-c1nc(c(NC(=O)N[C@@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)cc1C)-c1ccccc1

InChI Key InChIKey=OGIYYNGFEXVCHG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 445317   

TargetHigh affinity nerve growth factor receptor(Human)
Mochida Pharmaceutical

US Patent
LigandPNGBDBM445317(US10669239, Compound 44b)
Affinity DataIC50: 50nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent